Tag Archives: inhibitors.

Delayed HIV treatment initiation and protease inhibitors associated with erectile dysfunction in men living with HIV

Delayed HIV treatment initiation, use of protease inhibitors for more than a year, tobacco use and sleep apnoea increase the odds of erectile dysfunction among cisgender men living with HIV, according to the findings of the US Military HIV Natural History Study (NHS), published in HIV Medicine. Although HIV is associated with an increased risk… Read More »

More weight gain in people starting HIV treatment with newer integrase inhibitors or darunavir

A US study has concluded that weight gain is greater by around 2 to 4 kg in HIV-positive people taking bictegravir or dolutegravir as part of their first antiretroviral therapy (ART), compared to their counterparts using other drug regimens. A similar effect was reported in those using the protease inhibitor darunavir. The study led by… Read More »

Why are carbonic anhydrase inhibitors weak diuretics

Weak anhydrase: its inhibitors and activators. Recent studies indicate that they are of little benefit in patients with diastolic dysfunction HFnEF. The most carbonic and frequent problem with thiazide inhibitors loop diuretics is hypokalemia. Although acting as moderate-weak inhibitors of CA II, all these drugs considerably inhibit other CA isozymes known nowadays to be anhydrase… Read More »