Tag Archives: Optimization

Sustained Release Matrix Tablet of Tramadol HCl: Box-Behnken Design For Optimization of Formulation Variables of Tramadol HCl Sustained Release Matrix Tablet

To develop sustained release matrix tablet of Tramadol HCl that deliver drug for 24 hr and to be taken once in a day. Drug having high solubility and relatively shorter half-life suggests its suitability for an extended formulation. If it is formulated by conventional tablets, it will require multiple daily administrations which ultimately results into… Read More »