Perimenopausal

Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels

Women are at increased risk for depressive symptoms during the menopause transition. It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience declining levels of estrogen and progesterone during this transition, why is it that only some women suffer from depression in… Read More »

New Study at CWMH: A Neurosteroid Intervention for Menopausal and Perimenopausal Depression

Women are twice as likely as men to have major depressive disorder (MDD) during their lifetimes, and women are particularly at risk during the menopausal transition (including perimenopause and early menopause), which can last many years. Typically starting after age 40, this period is characterized by fluctuations in hormones and various physical symptoms like hot… Read More »