Tag Archives: Therapies

New “Old” Therapies in Pulmonary Arterial Hypertension: A Clinical Roundtable

Despite recent strides in elucidating the pathophysiology of pulmonary arterial hypertension (PAH), there have been few advances in the development of novel therapies to treat the disease. The medications currently approved for PAH treatment are most beneficial in the 5% to 10% of patients with PAH who are vasoresponders, although these therapies have been shown… Read More »

These Patients Had Sickle-Cell Disease. Experimental Therapies Might Have Cured Them.

Scientists have long known what causes sickle-cell disease and its devastating effects: a single mutation in one errant gene. But for decades, there has been only modest progress against an inherited condition that mainly afflicts people of African descent. With advances in gene therapy, that is quickly changing — so much so that scientists have… Read More »

Sensory neurons can be used to discover therapies for ALS

Virginia Tech Carilion Research Institute scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis — also known as ALS or Lou Gehrig’s disease — also attack sensory neurons. The discovery in today’s (Thursday, Nov. 8) Scientific Reports indicates that studying sensory neurons… Read More »